Fighting viruses in the heart of New York City since 2006
Infectious diseases still present a major threat to global health
Our mission is to build a safer world by understanding how people and viruses interact. As viruses change, we adapt to anticipate their next move.
Hidden viruses lurk in our genome - what are they up to?
Our team is discovering new methods of identifying active Human Endogenous Retroviruses (HERVs). Understanding HERVs could lead to crucial breakthroughs in human immune responses, cancer, and other autoimmune diseases.
HIV can lie dormant in your genome for decades but erupt at any moment. The Simon Lab at MSSM is finding ways to keep those viruses asleep.
How is HIV like a dormant volcano?
How long do antibodies to COVID-19 last?
In March 2024, our Director of Strategy and Operations, Komal Srivastava, joined CBS News to discuss our latest discovery that antibodies to COVID-19 are long-lasting.
Dr. Simon honored as a 2025 Jacobi Medallion recipient
This prestigious award honors a member of the Mount Sinai community who, through long-term service (typically 10 years or more), has made exceptional contributions to the fields of clinical medicine or biomedical research, or has exemplified extraordinary dedication to Mount Sinai.
"I can hardly imagine a point in time at which ambitious and creative virology research could be more important than it is right now. Congrats to all of you on your progress and on the growing recognition of the value of your efforts."
— Simon Lab Study Participant
